What is the most common clinical manifestation of gastroesophageal reflux?

Heartburn is the most common clinical manifestation of gastroesophageal reflux because it results from the acidic contents of the stomach flowing back into the esophagus. This reflux irritates the lining of the esophagus, leading to a burning sensation often described as heartburn. Patients typically report this discomfort after eating or when lying down, making it a classic symptom of the condition.

Nausea, abdominal pain, and chest tightness are also associated with gastroesophageal reflux but are not as prevalent or specific as heartburn. While some individuals may experience these other symptoms, heartburn stands out as the hallmark symptom that best characterizes this condition and is more frequently reported in clinical settings. Understanding this prominence of heartburn can help in diagnosing gastroesophageal reflux and guiding treatment for affected patients.